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An endometrial stromal nodule is a noninfiltrative, circumscribed proliferation of endometrial stromal cells and is a benign subtype of endometrial stromal tumor. The appearance of the cells is identical to normal endometrial stromal cells. This can only be differentiated from low-grade endometrial stromal sarcoma by confirming lack of ...
Stromal cells are an important part of the body's immune response and modulate inflammation through multiple pathways. They also aid in differentiation of hematopoietic cells and forming necessary blood elements. The interaction between stromal cells and tumor cells is known to play a major role in cancer growth and progression. [1]
Stromal tissue falls into the "functional" class that contributes to the body's support and movement. The cells which make up stroma tissues serve as a matrix in which the other cells are embedded. [2] Stroma is made of various types of stromal cells. Examples of stroma include: stroma of iris; stroma of cornea; stroma of ovary; stroma of ...
The corresponding specific proteins are expressed in the glandular and stromal cells of the endometrial mucosa. The expression of many of these proteins vary depending on the menstrual cycle, for example the progesterone receptor and thyrotropin-releasing hormone both expressed in the proliferative phase, and PAEP expressed in the secretory phase.
Surface epithelial-stromal tumors are labeled in center of the main diagram, and represent all types except the ones separated at top. Epithelial-stromal tumors are classified on the basis of the epithelial cell type, the relative amounts of epithelium and stroma, the presence of papillary processes, and the location of the epithelial elements.
The myometrium is located between the endometrium (the inner layer of the uterine wall) and the serosa or perimetrium (the outer uterine layer).. The inner one-third of the myometrium (termed the junctional or sub-endometrial layer) appears to be derived from the Müllerian duct, while the outer, more predominant layer of the myometrium appears to originate from non-Müllerian tissue and is ...
Well-differentiated adenocarcinomas tend to resemble the glandular tissue that they are derived from, while poorly differentiated adenocarcinomas may not. By staining the cells from a biopsy , a pathologist can determine whether the tumor is an adenocarcinoma or some other type of cancer.
Microglandular hyperplasia (MGH) of the cervix is an epithelial (endocervical mucosa) benign abnormality (lesion) associated with gland proliferation. [1] [2] It can terminate in mature squamous metaplasia, and it is suspected reserve cells are involved in this process, perhaps in the form of reserve cell hyperplasia with glandular differentiation.