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  2. Per-oral endoscopic myotomy - Wikipedia

    en.wikipedia.org/wiki/Per-oral_endoscopic_myotomy

    The per-oral endoscopic myotomy, or POEM, is a minimally invasive surgical procedure for the treatment of achalasia wherein the inner circular muscle layer of the lower esophageal sphincter is divided through a submucosal tunnel. [1] This enables food and liquids to pass into the stomach, a process that is impaired in achalasia.

  3. Botulinum toxin - Wikipedia

    en.wikipedia.org/wiki/Botulinum_toxin

    Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species. [24] It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. [25]

  4. Botox complications are rare. But what happens when an ... - AOL

    www.aol.com/botox-complications-rare-happens...

    Botox is a neuromodulator injection that's known for its ability to improve the appearance of fine lines and wrinkles when injected into the facial muscles, says Dr. Nayoung Lee, an assistant ...

  5. Esophageal achalasia - Wikipedia

    en.wikipedia.org/wiki/Esophageal_achalasia

    Botulinum toxin (botox) may be injected into the lower esophageal sphincter to paralyze the muscles holding it shut. As in the case of cosmetic botox, the effect is only temporary and lasts about 6 months. Botox injections cause scarring in the sphincter which may increase the difficulty of later Heller myotomy.

  6. Anal fissure - Wikipedia

    en.wikipedia.org/wiki/Anal_fissure

    A combined surgical and pharmacological treatment, administered by colorectal surgeons, is the direct injection of botulinum toxin (Botox) into the anal sphincter to relax it. This treatment was first investigated in 1993.

  7. Retrograde cricopharyngeal dysfunction - Wikipedia

    en.wikipedia.org/wiki/Retrograde_cricopharyngeal...

    It is a strap-like, C-shaped muscle at the base of the throat, behind the larynx. The upper esophageal sphincter encircles the proximal (upper) opening of the oesophagus. [9] The upper esophageal sphincter has a residual tone which is in fact augmented as it is stretched open. [10] Swallowing of air during eating and drinking is normal.

  8. Internal anal sphincter - Wikipedia

    en.wikipedia.org/wiki/Internal_anal_sphincter

    The internal anal sphincter, IAS, or sphincter ani internus is a ring of smooth muscle that surrounds about 2.5–4.0 cm of the anal canal. It is about 5 mm thick, and is formed by an aggregation of the smooth (involuntary) circular muscle fibers of the rectum.

  9. External anal sphincter - Wikipedia

    en.wikipedia.org/wiki/External_anal_sphincter

    The external anal sphincter (or sphincter ani externus) is an oval tube of skeletal muscle fibers. [1] Distally, it is adherent to the skin surrounding the margin of the anus. [2] It exhibits a resting state of tonical contraction [1] and also contracts during the bulbospongiosus reflex. [3] [4] [5] [6]