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  2. Why Early Diagnosis of PAH is So Important - AOL

    www.aol.com/why-early-diagnosis-pah-important...

    Oct. 31—(StatePoint) Each year, 500 to 1,000 people in the United States are diagnosed with pulmonary arterial hypertension (PAH). Because this progressive, chronic disorder is rare, it is often ...

  3. Phenylketonuria - Wikipedia

    en.wikipedia.org/wiki/Phenylketonuria

    The PAH gene is located on chromosome 12 in the bands 12q22-q24.2. [22] As of 2000, around 400 disease-causing mutations had been found in the PAH gene. This is an example of allelic genetic heterogeneity. [5]

  4. Pulmonary arterial hypertension - Wikipedia

    en.wikipedia.org/.../Pulmonary_arterial_hypertension

    PAH is further subdivided into various categories based on the cause, including idiopathic, heritable, drug and toxin induced, PAH associated with specific diseases (such as connective tissue disorders, portal hypertension or HIV), PAH that is responsive to vasodilators, PAH with venous or capillary involvement, and persistent PAH in the ...

  5. FDA approves new drug that may help stop a rare, fatal ... - AOL

    www.aol.com/fda-approves-drug-may-help-213035907...

    When doctors told Katrina Barry that she had a rare and serious condition called pulmonary arterial hypertension, ... were dealing with PAH, she said. Because the disease is rare and often affects ...

  6. Merck's therapy for rare lung condition shown to help reduce ...

    www.aol.com/news/mercks-therapy-rare-lung...

    Winrevair was approved to treat pulmonary arterial hypertension (PAH), a progressive disorder caused by a constriction of arteries in the lungs, leading to symptoms such as shortness of breath ...

  7. Pulmonary hypertension - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_hypertension

    Pulmonary hypertension is defined as a mean PAP of at least 20 mm Hg (3300 Pa) at rest, and PAH is defined as precapillary pulmonary hypertension (i.e. mean PAP ≥ 20 mm Hg with pulmonary arterial occlusion pressure [PAOP] ≤ 15 mm Hg and pulmonary vascular resistance [PVR] > 3 Wood Units). [58]

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