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  2. Cocaine dependence - Wikipedia

    en.wikipedia.org/wiki/Cocaine_dependence

    Cocaine is a powerful stimulant known to make users feel energetic, cheerful, talkative, etc. In time, negative side effects include increased body temperature, irregular or rapid heart rate, high blood pressure, increased risk of heart attacks, strokes and even sudden death from cardiac arrest.

  3. Drug withdrawal - Wikipedia

    en.wikipedia.org/wiki/Drug_withdrawal

    Drug withdrawal, drug withdrawal syndrome, or substance withdrawal syndrome [1] is the group of symptoms that occur upon the abrupt discontinuation or decrease in the intake of pharmaceutical or recreational drugs. In order for the symptoms of withdrawal to occur, one must have first developed a form of drug dependence.

  4. Addiction psychology - Wikipedia

    en.wikipedia.org/wiki/Addiction_psychology

    The latter reflects physical dependence in which the body adapts to the drug, requiring more of it to achieve a certain effect (tolerance) [25] and eliciting drug-specific physical or mental symptoms if drug use is abruptly ceased (withdrawal). Physical dependence can happen with the chronic use of many drugs—including even appropriate ...

  5. Reverse tolerance - Wikipedia

    en.wikipedia.org/wiki/Reverse_tolerance

    dependence – an adaptive state associated with a withdrawal syndrome upon cessation of repeated exposure to a stimulus (e.g., drug intake) drug sensitization or reverse tolerance – the escalating effect of a drug resulting from repeated administration at a given dose; drug withdrawal – symptoms that occur upon cessation of repeated drug use

  6. Cocaine - Wikipedia

    en.wikipedia.org/wiki/Cocaine

    Cocaine (from French cocaïne, from Spanish coca, ultimately from Quechua kúka) [13] is a tropane alkaloid that acts as a central nervous system (CNS) stimulant. As an extract, it is mainly used recreationally and often illegally for its euphoric and rewarding effects.

  7. Drug rehabilitation - Wikipedia

    en.wikipedia.org/wiki/Drug_rehabilitation

    Motivational incentives, which uses positive reinforcement to encourage abstinence from the addictive substance. [ 10 ] EEG Biofeedback augmented treatment improves abstinence rates of 12-step, faith-based, and medically assisted addiction for cocaine, methamphetamine, alcohol use disorder, and opioid addictions.

  8. Substance dependence - Wikipedia

    en.wikipedia.org/wiki/Substance_dependence

    Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...

  9. Comedown (drugs) - Wikipedia

    en.wikipedia.org/wiki/Comedown_(drugs)

    For example, in an MDMA ("ecstasy" and "molly") comedown, if the user experiences severe, persisting emotional distress, such as panic attacks, severe generalized anxiety, or insomnia following an MDMA session, a physician may prescribe a benzodiazepine (specifically, lorazepam) and/or sleep aid (e.g., zolpidem), to alleviate those effects.