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Ehrlichiosis (/ ˌ ɛər l ɪ k i ˈ oʊ s ɪ s /; also known as canine rickettsiosis, canine hemorrhagic fever, canine typhus, tracker dog disease, and tropical canine pancytopenia) is a tick-borne disease of dogs usually caused by the rickettsial agent Ehrlichia canis. Ehrlichia canis is the pathogen of animals.
Tick control is the main preventive measure against the disease. However, in late 2012, a breakthrough in the prevention of canine monocytic ehrlichiosis was announced when a vaccine was accidentally discovered by Prof. Shimon Harrus, Dean of the Hebrew University of Jerusalem's Koret School of Veterinary Medicine. [18]
E. canis is a small, coccus bacterium with a single circular chromosome.Minute in size, E. canis is smaller than the other species in the genus Ehrlichia. [8] [10]The cell walls of this organism lack peptidoglycans and lipopolysaccharides typically present in at least small amounts in most other Gram-negative bacteria, which is believed to contribute to its ability to resist the immune ...
In 1945, an "infection and treatment" method for livestock was developed. This is still the only commercially available "vaccine" against the disease, which is not a true vaccine, but intentional exposure to the disease with monitoring and antibiotic treatment if needed. In 1985, the organism was first propagated reliably in tissue culture.
Ehrlichiosis, the disease caused by E. ewingii and E. chaffeensis, presents with fever, headache, fatigue, and muscle aches. [8] These symptoms are extremely unspecific which makes the infections difficult to diagnose. [8] Doxycycline is effective when administered early in the infection, but despite this, the estimated fatality rate is still 1 ...
For Anaplasmosis, ehrlichiosis and Rocky Mountain spotted fever, Doxycycline is the first line treatment for adults and children of all ages. For babesiosis, a combination therapy with atovaquone and azithromycin is most commonly recommended for treatment of mild to moderate babesiosis. Treatment is usually continued for 7 to 10 days.