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MELAS is a condition that affects many of the body's systems, particularly the brain and nervous system (encephalo-) and muscles (myopathy). In most cases, the signs and symptoms of this disorder appear in childhood following a period of normal development. [ 4 ]
The most prevalent endocrine pathology in MELAS syndrome includes diabetes mellites, predominately Type 1, present in 21-33% of patients. This occurs as a result of insulin production deficiency due to damaged pancreatic beta cells , insulin section impairments, and increased gluconeogenesis .
MELAS is a rare mitochondrial disorder known to affect many parts of the body, especially the nervous system and the brain. Symptoms of MELAS include recurrent severe headaches , muscle weakness ( myopathy ), hearing loss , stroke -like episodes with a loss of consciousness , seizures , and other problems affecting the nervous system . [ 6 ]
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Includes Mitochondrial Encephalitis Lactic Acidosis Seizures (MELAS), myoclonic epilepsy and ragged red fibers (MERRF), maternally inherited Leigh syndrome (MILS), and mitochondrial neurograstrointestinal encephalomyopathy (MNGIE), all of which can all develop optic neuropathies, although it is usually a secondary feature overshadowed by more ...
Lambert–Eaton myasthenic syndrome (LEMS) is an autoimmune condition that attacks the neuromuscular junction, either as a paraneoplastic syndrome (typically older patients) or associated with a non-cancerous primary autoimmune condition (typically younger patients). It usually involves lower limb weakness and exercise-induced fatiguability ...
Mitochondrial disease Diabetes and deafness ( DAD ) or maternally inherited diabetes and deafness ( MIDD ) or mitochondrial diabetes is a subtype of diabetes which is caused from a mutation in mitochondrial DNA , which consists of a circular genome.
Neoglyphidodon melas, also known as the bowtie damselfish, black damsel, bluefin or royal damsel, is a species of damselfish found in the Indo-West Pacific. [1] It grows to a size of 18 cm (7.1 in) in length.