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Extracts from Camptotheca (the "happy tree" or "cancer tree") were used to develop the chemotherapeutic drug Topotecan. Plant sources of anti-cancer agents are plants, the derivatives of which have been shown to be usable for the treatment or prevention of cancer in humans. [1] [2]
The leaves are used as herbal medicine to alleviate cough and fever, pain, and general gastrointestinal disorders as well as to cure dermatologic disorders. Similarly, the fruit juice and oils can be used in the treatment of liver disease, gastrointestinal disorders, chronic wounds or other dermatological disorders. [86] Hoodia gordonii: Hoodia
The polysaccharides of Wolfiporia extensa and their derivatives have garnered significant interest due to their wide range of biological activities. These compounds exhibit potent anticancer, anti-inflammatory, antioxidant, and antiviral effects, which indicate their potential for further development as therapy or adjuvant therapy for cancer, immune modulation, and viral diseases.
This belief that generally boosting the immune system's activity will kill the cancer cells is not supported by any scientific research. [51] In fact, many cancers require the support of an active immune system (especially through inflammation) to establish the tumor microenvironment necessary for a tumor to grow.
Hinokinin is a dibenzylbutyrolactone lignan, derived from various species of plants.It is a potential antichagonistic agent. [1] In vitro, it has been shown to have potential neuroprotective effects [2] as well as anti-inflammatory, anti-tumor, antiviral and antifungal properties.
Among these effects are antimicrobial activity, [33] [34] antiviral activity [35] and antineoplastic activity, [36] [37] acetylcholinesterase inhibition, [38] [39] and gastric ulcers treatment. [40] Antimicrobial activity of several PAs have been identified as having mild to strong effect against bacteria: E. coli and P. chrysogenum. [33]
Research showed that palmatine had broad anti-cancer activity. Palmatine had significant growth inhibitory effects on seven human cancer cell lines: 7701QGY, SMMC7721, HepG2, CEM, CEM/VCR, K III and Lewis. [17] In addition, palmatine also had anti-cancer activity on MCF-7, U251, KB, [18] CHOK-1, HT-29 and SiHacell lines. [19]
The botanical herbal market has been criticized for being poorly regulated and containing placebo and pseudoscience products with no scientific research to support their medical claims. [4] Medicinal plants face both general threats, such as climate change and habitat destruction , and the specific threat of over-collection to meet market demand.