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[14] [12] However, all NSAIDs showed association with structural cardiac defects with usage during the early weeks of pregnancy. When ibuprofen and naproxen are used within the third trimester, there is a significant increase in the risk of premature closure of the ductus arteriosus with primary pulmonary hypertension in the newborn. [ 12 ]
Women with placenta previa often present with painless, bright red vaginal bleeding. This commonly occurs around 32 weeks of gestation, but can be as early as late mid-trimester. [8] More than half of women affected by placenta praevia (51.6%) have bleeding before delivery. [9]
Women who have high blood pressure or who have had a previous placental abruption and want to conceive must be closely supervised by a doctor. [ 17 ] The risk of placental abruption can be reduced by maintaining a good diet including taking folate , regular sleep patterns and correction of pregnancy-induced hypertension .
Women who endured placental disease within the first pregnancy has an increased risk of the disease progressing within future pregnancies. [13] The onset of the disease within the first trimester leads to preterm delivery of a premature baby. [ 14 ]
Placental abruption defined as the separation of the placenta from the uterus prior to delivery, is a major cause of third trimester vaginal bleeding and complicates about 1% of pregnancies. [13] [50] Symptomatic presentations are variable: Some women can entirely ignore the symptoms, while others have mild bleeding or abdominal discomfort and ...
If placenta previa is present at the time of delivery, vaginal delivery is contraindicated because the placenta is blocking the fetus's passageway to the vaginal canal. Herpes simplex virus with active genital lesions or prodromal symptoms is a contraindication for vaginal delivery so as to avoid mother-fetal transfer of HSV lesions.
Other adverse effects may include nausea, vomiting, fever, chills, diarrhea, headache, dizziness, warmth or hot flashes. [50] [43] [20] When used inside the vagina, misoprostol tends to have fewer gastrointestinal side effects. [6] Nonsteroidal anti-inflammatory medications such as ibuprofen reduce pain with medication abortion.
Signs and symptoms of pregnancy are common, benign conditions that result from the changes to the body that occur during pregnancy. Signs and symptoms of pregnancy typically change as pregnancy progresses, although several symptoms may be present throughout. Depending on severity, common symptoms in pregnancy can develop into complications. [1]