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CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder. The acronym "CREST" refers to the five main features: calcinosis , Raynaud's phenomenon , esophageal dysmotility , sclerodactyly , and telangiectasia .
One form of the condition, known as CREST syndrome, classically results in calcium deposits, Raynaud's syndrome, esophageal problems, thickening of the skin of the fingers and toes, and areas of small, dilated blood vessels. [1] The cause is unknown, but it may be due to an abnormal immune response. [2]
Sclerodactyly is one component of the limited cutaneous form of systemic sclerosis (lcSSc), also known as CREST syndrome (CREST is an acronym that stands for calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.) [4] Sclerodactyly is also one component of Huriez Syndrome, along with palmoplantar ...
Other conditions may mimic systemic sclerosis by causing hardening of the skin. Diagnostic hints that another disorder is responsible include the absence of Raynaud's phenomenon, a lack of abnormalities in the skin on the hands, a lack of internal organ involvement, and a normal antinuclear antibodies test result.
Pervasive developmental disorder: PDD-NOS Pervasive developmental disorder, not otherwise specified: PDD/NOS Pervasive developmental disorder, not otherwise specified: PDS Pokkuri Death Syndrome PE Pulmonary embolism: PKAN Panthothenate kinase-associated neurodegeneration: PLMD Periodic limb movement disorder: PLS Primary lateral sclerosis: PMD
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According to the Centers for Disease Control and Prevention, it is a serious medical condition that can result in death or disability. Rhabdo happens when damaged muscle tissue releases proteins ...
A small percentage of cases result from spontaneous new mutations in the gene, where no family history of the condition exists. [citation needed] The neural crest is a group of temporary migratory cells that are left over after the neural tube has closed (neurulation), around the fourth week of embryonic development. They are responsible for ...