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Diabetes was linked to the concurrent use of mycophenalate mofetil in patients with lupus receiving high-dose steroid therapy; this could be explained by decreased insulin secretion due to elevated beta cell stress. [3] [4] There is an inverse correlation between serum magnesium levels and glycemic control, according to several studies. [5]
It can also cause depression or depressive symptoms and anxiety in some individuals. [ 25 ] [ 26 ] Long-term side effects include Cushing's syndrome , steroid dementia syndrome , [ 27 ] truncal weight gain, glaucoma and cataracts , diabetes mellitus type 2 , and depression upon dose reduction or cessation. [ 28 ]
Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. [4] [9] [10] Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face due to facial plethora, [11] a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals ...
"This can cause leaky gut syndrome and increase inflammation and oxidative stress," says Alexander. ... Diabetes medications: Insulin and thiazolidinediones ... Glucocorticoids: Prednisone and ...
Metformin itself isn’t thought to cause hair loss, but type 2 diabetes and PCOS (polycystic ovary syndrome) — the conditions it’s prescribed to treat — can cause hair loss.
Prednisone hair loss isn’t a proven side effect. However, the FDA notes that some formulations of the medication may cause hair thinning. Prednisone can actually treat some forms of hair loss ...
Glucocorticoids cause immunosuppression, and the therapeutic component of this effect is mainly the decreases in the function and numbers of lymphocytes, including both B cells and T cells. The major mechanism for this immunosuppression is through inhibition of nuclear factor kappa-light-chain-enhancer of activated B cells ( NF-κB ).
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