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The book characterizes the inability of humans and some other animals to produce vitamin C (ascorbic acid) in terms of evolution and Pauling's concept of "molecular disease" (first articulated in his 1949 study, "Sickle Cell Anemia, a Molecular Disease"). Pauling argues that the loss of vitamin C synthesis first arose as a molecular disease ...
The Linus Pauling Institute still exists, but moved in 1996 from Palo Alto, California, to Corvallis, Oregon, where it is part of the Linus Pauling Science Center at Oregon State University. [ 181 ] [ 182 ] [ 183 ] The Valley Library Special Collections at Oregon State University contain the Ava Helen and Linus Pauling Papers, including ...
In the 1960s, Linus Pauling, after contact with Irwin Stone, [91] began actively promoting vitamin C as a means to greatly improve human health and resistance to disease. The Pauling's book How to Live Longer and Feel Better, [92] first published in 1986, [93] was a bestseller and advocated taking more than 10 grams per day orally, thus ...
In the late 1960s, Linus Pauling introduced the expression "orthomolecular" [11] to express the idea of the right molecules in the right amounts. [11] Since the first claims of medical breakthroughs with vitamin C by Pauling and others, findings on the health effects of vitamin C have been controversial and contradictory.
While at Caltech, Itano joined the lab of Linus Pauling and began working on sickle cell anemia, a genetic disease that Pauling was interested in. [4] Pauling was convinced that sickle cell disease was caused by defective hemoglobin, and set Itano to find out what made sickle cell hemoglobin chemically different. [9]
The Linus Pauling Institute is a research institute located at the Oregon State University with a focus on health maintenance. The mission statement of the institute is to determine the functional roles of micronutrients and phytochemicals in promoting optimal health and to treat or prevent human disease, and to determine the role of oxidative stress and inflammation in health and disease.
The molecular disease concept put forward in the 1949 paper also became the basis for Linus Pauling's view of evolution. In the 1960s, by which time it had been shown that sickle cell trait confers resistance to malaria and so the gene had both positive and negative effects and demonstrated heterozygote advantage , Pauling suggested that ...
He subsequently joined two-time Nobel Prize laureate Linus Pauling at his research institute in California. [22] Ultimately, Rath had a falling-out with the Linus Pauling Institute; after a series of lawsuits and countersuits, Rath was ordered in 1994 to pay the Institute $75,000 and was assigned several patents. [6]