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[18] [20] At the time, Alles referred to the amphetamine compound as Benzedrine, a term derived from the name benzyl-methyl carbinamine. [21] In 1934, Smith, Kline & French made the first amphetamine pharmaceutical when they began selling a decongestant inhaler containing the volatile amphetamine free base under the trade name Benzedrine.
Propylhexedrine, sold under the brand name Benzedrex among others, is a nasal decongestant of the alkylamine family and related to the arylalkylamines. [1] Its main indications are relief of congestion due to colds, allergies, and allergic rhinitis. [2]
Amphetamine had no medical use until late 1933, when Smith, Kline and French began selling it as an inhaler under the brand name Benzedrine as a decongestant. [30] Benzedrine sulfate was introduced 3 years later and was used to treat a wide variety of medical conditions , including narcolepsy , obesity , low blood pressure , low libido , and ...
Notably, the amphetamine contained in the Benzedrine inhaler was the liquid free-base, [note 14] not a chloride or sulfate salt. Three years later, in 1935, the medical community became aware of the stimulant properties of amphetamine, specifically the dextroamphetamine isomer, and in 1937 Smith, Kline, and French introduced tablets under the ...
This procedure often lead to severe headaches that Dr. Bradley assumed, resulted from the loss of Cerebrospinal fluid. In an attempt to stimulate the choroid plexus and produce more of the fluid Bradley prescribed Benzedrine, a brand name for Amphetamine sold as an inhaler. It was then noted by the teachers and nurses who cared for the children ...
The first patented amphetamine brand, Benzedrine, was a racemic (i.e., equal parts) mixture of the free bases or the more stable sulfate salts of both amphetamine enantiomers (levoamphetamine and dextroamphetamine) that was introduced in the United States in 1934 as an inhaler for treating nasal congestion. [2]
Amphetamine was developed by Smith, Kline and French as a nasal decongestant under the trade name Benzedrine Inhaler. Amphetamine was eventually developed for the treatment of narcolepsy , post-encephalitic parkinsonism , and mood elevation in depression and other psychiatric indications.
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