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Fig.1) Schematic diagram of the nephron (yellow), relevant circulation (red/blue), and the four methods of altering the filtrate. The nephron is the functional unit of the kidney. [3] This means that each separate nephron is where the main work of the kidney is performed. A nephron is made of two parts:
The nephron by itself is similar to pronephros as a whole organ. [18] The simplest nephrons are found in the pronephros, which is the final functional organ in primitive fish . [ 19 ] The nephrons of the mesonephros, the functional organ in most anamniotes called opisthonephros , [ 20 ] are slightly more complex than those of the pronephros. [ 19 ]
[10] [11] [12] The left kidney is approximately at the vertebral level T12 to L3, [13] and the right is slightly lower. The right kidney sits just below the diaphragm and posterior to the liver. The left kidney sits below the diaphragm and posterior to the spleen. On top of each kidney is an adrenal gland.
Each nephron begins in a renal corpuscle, which is composed of a glomerulus enclosed in a Bowman's capsule. Cells, proteins, and other large molecules are filtered out of the glomerulus by a process of ultrafiltration , leaving an ultrafiltrate that resembles plasma (except that the ultrafiltrate has negligible plasma proteins ) to enter Bowman ...
The epithelium in the thick segment of the descending limb consists of low simple cuboidal cells, which resemble those found in the proximal tubule.In contrast, the epithelium transitions to a simple squamous type in the thin segment, which is less metabolically active and has minimal surface specializations.
English: A modern illustration of the basic physiology of a nephron within a kidney. The labels are: 1. Glomerulus, 2. Efferent arteriole, 3. Bowman's capsule, 4. Proximal tube, 5.
Diagram outlining movement of ions in nephron, with the collecting ducts on the right. The collecting duct system is the final component of the kidney to influence the body's electrolyte and fluid balance. In humans, the system accounts for 4–5% of the kidney's reabsorption of sodium and 5% of the kidney's reabsorption of water. At times of ...
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