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Tretinoin/benzoyl peroxide, sold under the brand name Twyneo, is a fixed-dose combination medication used for the treatment of acne. [1] [2] It contains tretinoin, a vitamin A derivative, and benzoyl peroxide, an oxidizing agent. [3] The combination was approved for medical use in the United States in July 2021. [2] [4] [5]
The origin of the name tretinoin is uncertain, [42] [43] although several sources agree (one with probability, [42] < one with asserted certainty [44]) that it probably comes from trans-+ retinoic [acid] + -in, which is plausible given that tretinoin is the all-trans isomer of retinoic acid. The name isotretinoin is the same root tretinoin plus ...
Fluocinolone acetonide (0.01%)/Hydroquinone (4%)/ Tretinoin (0.05%) Cream is indicated for the short-term (up to 8 weeks) treatment of moderate to severe melasma of the face in the presence of measures for sun avoidance, including the use of sunscreens.
Clindamycin/tretinoin is a topical gel used in the treatment of acne. The two active ingredients are the antibiotic clindamycin phosphate (1.2%) and tretinoin (0.025%), a retinoid . [ 1 ] The two active ingredients perform different functions, the clindamycin is active against gram-positive bacteria, including streptococci and penicillin ...
1st, 2nd, 3rd-generation retinoid compounds. The retinoids are a class of chemical compounds that are natural derivatives of vitamin A or are chemically related to it. . Synthetic retinoids are utilized in cosmetic formulations, clinical dermatology, and the treatment of some forms o
Topical cream formulation is an emulsion semisolid dosage form that is used for skin external application. Most of the topical cream formulations contain more than 20 per cent of water and volatiles and/or less than 50 per cent of hydrocarbons , waxes , or polyethylene glycols as the vehicle for external skin application. [ 1 ]
Mequinol is a common active ingredient in topical drugs used for skin depigmentation.As a topical drug mequinol is often mixed with tretinoin, a topical retinoid.A common formulation for this drug is an ethanolic solution of 2% mequinol and 0.01% tretinoin by mass. [1]
The combination tretinoin/benzoyl peroxide was approved for medical use in the United States in 2021. Benzoyl peroxide for acne treatment is typically applied to the affected areas in gel, cream, or liquid, in concentrations of 2.5% increasing through 5.0%, and up to 10%. [28]