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Estradiol, the base estrogen of most estrogen esters. This is a list of estrogen esters, or ester prodrugs of estrogens. It includes esters, as well as ethers, of steroidal estrogens like estradiol, estrone, and estriol and of nonsteroidal estrogens like the stilbestrols diethylstilbestrol and hexestrol.
[32] [33] [34] Estradiol is also used as other prodrugs, like estradiol cypionate. [11] Related estrogens such as ethinylestradiol, which is the most common estrogen in birth control pills, and conjugated estrogens (brand name Premarin), which is used in menopausal hormone therapy, are used as medications as well. [11]
Estradiol cypionate (Depo-Estradiol, Estradiol Cypionate) – 5 mg/mL (1 mg/mL and 3 mg/mL discontinued) Estradiol valerate (Delestrogen, Estradiol Valerate) – 10 mg/mL, 20 mg/mL, 40 mg/mL; Polyestradiol phosphate (Estradurin) was previously available in the U.S. but was discontinued.
This is a list of investigational sex-hormonal agents, ... EC508 – oral prodrug of estradiol with improved pharmacokinetics [1] [8] [2]
This is a list of steroidal estrogens or derivatives of estradiol, estrone, and estriol. ... Estradiol 17β-chloral hemiacetal ether O,O-diacetate
The drug shows reduced susceptibility to first-pass metabolism relative to estradiol, and was believed to be the first "potent" estradiol prodrug to be discovered. [ 3 ] [ 4 ] [ 8 ] Unlike estradiol and other estradiol esters, due to its unique sulfamate ester, E2MATE is not hydrolyzed during the first pass with oral administration, and instead ...
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