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10x Genomics was founded in 2012 by Serge Saxonov, Ben Hindson and Kevin Ness to create advanced testing equipment for use in cellular biology. [3] Prior to starting the company, Saxonov was the founding architect, and director of research and development at 23andMe. [2]
Previous efforts of coupling index-sorting measurements from single cell sorts with scRNA-seq were limited to running a small sample size and were not compatible with multiplexing and massive parallel high-throughput sequencing. CITE-seq has been shown to be compatible with high-throughput microfluidic platforms like 10X Genomics and Drop-seq ...
The 10X Genomics Visium assay is a newer and improved version of the Spatial Transcriptomics assay. It also utilizes spotted arrays of mRNA-capturing probes on the surface of glass slides but with increased spot number, minimized spot size and increased amount of capture probes per spot.
10x or 10X may refer to: 10x Management, an American talent management company; 10x Genomics, an American biotechnology company; Windows 10X, an abandoned edition of Microsoft's operating system; A grade of powdered sugar fineness; Zeolite 10X, a calcium-type molecular sieve with faujasite framework structure
Following this lawsuit, 10x Genomics discontinued their linked-read assay. [15] An exception was made for linked-read products which had already been sold by the company prior to the lawsuit, allowing 10x Genomics to continue to provide those researchers with services such as support and warranty maintenance for this technology. [citation needed]
This page was last edited on 19 November 2019, at 13:20 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
Most cellular deconvolution algorithms consider an input data in a form of a matrix , which represents some molecular information (e.g. gene expression data or DNA methylation data) measured over a group of samples and marks (e.g. genes or CpG sites).
V(D)J recombination (variable–diversity–joining rearrangement) is the mechanism of somatic recombination that occurs only in developing lymphocytes during the early stages of T and B cell maturation.