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Human parvovirus B19, generally referred to as B19 virus (B19V), parvovirus B19 [1] or sometimes erythrovirus B19, [2] is a known human virus in the family Parvoviridae, genus Erythroparvovirus; it measures only 23–26 nm in diameter. [3] Human parvovirus b19 is a below-species classification of Erythroparvovirus primate1. [4]
According to the CDC, the parvovirus B19 infection rate was less than a 3% in all age groups from 2022 to June 2024. Then in June , the infection rate suddenly jumped to 10%.
Parvovirus B19 will start replicating from anywhere for four to eighteen days. Infected children will be most contagious during this time and before they develop the most notable sign, a red rash on their cheeks, and other symptoms. [4] Since parvovirus B19 is a single stranded DNA virus, replication can only occur in dividing cells. [8]
The prevalence of parvovirus B19 in pooled plasma samples from an unspecified “large commercial laboratory” increased from 1.5% in December to 19.9% in June, the CDC said.
The following is a differential diagnosis for patients in which reticulocytopenia is the most marked cytopenia. For conditions that lead to significant reduction in all three cell lineages, see pancytopenia or aplastic anemia. Parvovirus B19 infection [5] Transient Erythroblastopenia of Childhood [4] Pure red cell aplasia [6]
Parvovirus B19 is highly infectious. Half of the people exposed in one household can become infected, the CDC said. Similar numbers are seen at schools among students and staff during outbreaks.
Symptoms of parvovirus B19 come in phases. Many people infected with the virus are asymptomatic or have very mild symptoms. For people who do experience symptoms, the first phase of illness ...
In pigs, the porcine parvovirus is a major cause of infertility. Human parvoviruses are less severe, the two most notable being parvovirus B19, which causes a variety of illnesses including fifth disease in children, and human bocavirus 1, which is a common cause