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Rupatadine is a second generation antihistamine and platelet-activating factor antagonist used to treat allergies. It was discovered and developed by Uriach [ es ] [ 3 ] and is marketed as Rupafin and under several other trade names.
Terfenadine is an antihistamine formerly used for the treatment of allergic conditions. It was brought to market by Hoechst Marion Roussel (now Sanofi) and was marketed under various brand names, including Seldane in the United States, Triludan in the United Kingdom, and Teldane in Australia. [1]
Antifungal medications that target ergosterol synthesis are selectively toxic to the fungi, hence, killing and stopping the growth of fungi in the body. When ergosterol is damaged, it causes the contents inside the fungal cells to leak out, preventing further reproduction of fungal cells. Lastly, antifungal agents contribute to fungal cell death.
Antifungal resistance is a One Health concern, driven by multiple extrinsic factors, including extensive fungicidal use, overuse of clinical antifungals, environmental change and host factors. [ 1 ] Like resistance to antibacterials, antifungal resistance can be driven by antifungal use in agriculture.
Anti-inflammatory drugs and immunomodulatory agents such as dapsone, hydroxychloroquine, cyclosporine, interferon alfa, tacrolimus, TNF inhibitors, various antifungal agents, and numerous other agents [18] have been used to treat the disorder in case reports but their value in treating the disorder as well as mosquito bite allergies is unclear ...
Plants need to defend themselves from attack by micro-organisms, in particular fungi, and they do this by producing anti-fungal chemicals that are toxic to fungi. Because fungal and human cells are similar at a biochemical level it is often the case that chemical compounds intended for plant defence have an inhibitory effect on human cells ...