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Colgate Dental Cream (toothpaste) with Gardol c. 1950s Colgate is an American brand principally used for oral hygiene products such as toothpastes , toothbrushes , mouthwashes and dental floss . Manufactured by Colgate-Palmolive , Colgate's oral hygiene products were first sold by the company in 1873, sixteen years after the death of the ...
In 1950, under sponsorship of the manufacturer of the compounds, Ozark Chemical Company, the toxicity of sodium monofluorophosphate was studied by Harold Hodge at the University of Rochester who included anti-cavity testing. In 1967 Colgate-Palmolive filed several patents on the use of sodium monofluorophosphate in toothpaste. [4]
Close-Up: marketed by Unilever, [12] it was launched in 1967 and was the first gel toothpaste in the world. [13] Colgate: marketed by Colgate-Palmolive, it is the first toothpaste in a collapsible tube, introduced in 1896, after having been sold in glass jars since 1873. [14]
The agency believes that the information contained in its adverse reaction files, 30 years of safe marketing of an OTC mouthwash containing cetylpyridinium chloride (NDA 14- 598), and the safety data evaluated by the Oral Cavity Panel are sufficient to conclude that 0.025 to 0.1 percent cetylpyridinium chloride is safe as an OTC oral antiseptic ...
Toothpaste is a paste or gel dentifrice used with a toothbrush to clean and maintain the aesthetics and health of teeth. Toothpaste is used to promote oral hygiene : it is an abrasive that aids in removing dental plaque and food from the teeth, assists in suppressing halitosis , and delivers active ingredients (most commonly fluoride ) to help ...
Later, the fluoride is re-released into the oral cavity from these reservoirs which acts as protection for the teeth against cavities. [36] Currently, there is also no published evidence that indicates that professionally applied fluoride varnish is a risk factor for enamel fluorosis .