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B-cell chronic lymphocytic leukemia/small cell lymphoma; 3–4% of lymphomas in adults Small resting lymphocytes mixed with variable numbers of large activated cells, lymph nodes diffusely effaced CD5, surface immunoglobulin 5-year survival rate 50%. [33]
Venetoclax, sold under the brand names Venclexta and Venclyxto, is a medication used to treat adults with chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), or acute myeloid leukemia (AML).
Five account for nearly three out of four patients with non-Hodgkin lymphoma: [3] Diffuse large B-cell lymphoma (DLBCL) [4] Follicular lymphoma; Marginal zone B-cell lymphoma (MZL) or mucosa-associated lymphatic tissue lymphoma (MALT) Small lymphocytic lymphoma (SLL, also known as chronic lymphocytic leukemia, CLL) Mantle cell lymphoma (MCL)
The five-year survival rate in the United States is 88.4%. [14] FL is the most prevalent form of indolent lymphoma, accounting for 70% of indolent cases and 20–30% of all non-Hodgkin lymphoma cases, with a yearly incidence of 1.6 to 3.1 per 100,000.
T-PLL is a very rare leukemia, primarily affecting adults over the age of 30. It represents 2% of all small lymphocytic leukemias in adults. [2] Other names include T-cell chronic lymphocytic leukemia, "knobby" type of T-cell leukemia, and T-prolymphocytic leukemia/T-cell lymphocytic leukemia. [1]
If CLL-type cells are mainly found in the lymph nodes or lymphoid tissue (such as the spleen), a diagnosis of small lymphocytic lymphoma (SLL) is made. [43] However, when these cancerous cells appear mostly in the blood, the disease is classified as CLL. [43] [44]