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Antiprotozoal agents (ATC code: ATC P01) is a class of pharmaceuticals used in treatment of protozoan infection. A paraphyletic group , protozoans have little in common with each other. For example, Entamoeba histolytica , a unikont eukaryotic organism, is more closely related to Homo sapiens (humans), which also belongs to the unikont ...
The severity of the infection can be lessened by treatment with antiprotozoal drugs like buparvaquone. Toxoplasma causes toxoplasmosis and can be acquired from undercooked meat or cat feces containing Toxoplasma gondii. The majority of the 60 million Americans infected with T. gondii are asymptomatic. The group most vulnerable to this pathogen ...
Biology portal Subcategories. This category has only the following subcategory. ... Pages in category "Antiprotozoal agents" The following 70 pages are in this ...
Clioquinol (iodochlorhydroxyquin) tradename Entero-Vioform is an antifungal drug and antiprotozoal drug. It is neurotoxic in large doses. It is a member of a family of drugs called hydroxyquinolines which inhibit certain enzymes related to DNA replication. The drugs have been found to have activity against both viral and protozoal infections. [2]
A limited number of antibiotics also possess antiprotozoal activity. [3] [4] Antibiotics are not effective against viruses such as the ones which cause the common cold or influenza. [5] Drugs which inhibit growth of viruses are termed antiviral drugs or antivirals. Antibiotics are also not effective against fungi.
Because many fungi and protozoa cannot survive without ergosterol, the enzymes that synthesize it have become important targets for drug discovery. In human nutrition, ergosterol is a provitamin form of vitamin D 2 ; exposure to ultraviolet (UV) light causes a chemical reaction that produces vitamin D 2 .
It is approved in the United States as a treatment and preventive measure against malaria. [6] The combination is considered to be more effective in treating malaria caused by Plasmodium falciparum than that caused by P. vivax, for which chloroquine is considered more effective, though in the absence of a species-specific diagnosis, the sulfadoxine-pyrimethamine combination may be indicated. [7]
Antiparasitics are one of the antimicrobial drugs which include antibiotics that target bacteria, and antifungals that target fungi. They may be administered orally, intravenously or topically. [4] Overuse or misuse of antiparasitics can lead to the development of antimicrobial resistance.