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In medicine, X-linked dominant inheritance indicates that a gene responsible for a genetic disorder is located on the X chromosome, and only one copy of the allele is sufficient to cause the disorder when inherited from a parent who has the disorder. In this case, someone who expresses an X-linked dominant allele will exhibit the disorder and ...
X-linked dominant traits can affect females as much as males. X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome. As an inheritance pattern, it is less common than the X-linked recessive type.
As a result, X-linked dominant disorders usually show higher expressivity in males than females. [ citation needed ] As the X chromosome is one of the sex chromosomes (the other being the Y chromosome ), X-linked inheritance is determined by the sex of the parent carrying a specific gene and can often seem complex.
[1] [2] Complications can include anemia and newborn jaundice. [2] Some people never have symptoms. [3] It is an X-linked recessive disorder that results in defective glucose-6-phosphate dehydrogenase enzyme. [1] Glucose-6-phosphate dehydrogenase is an enzyme that protects red blood cells, which carry oxygen from the lungs to tissues throughout ...
X-linked recessive inheritance. X-linked recessive inheritance is a mode of inheritance in which a mutation in a gene on the X chromosome causes the phenotype to be always expressed in males (who are necessarily hemizygous for the gene mutation because they have one X and one Y chromosome) and in females who are homozygous for the gene mutation (see zygosity).
X-linked dominant inheritance; A. Aicardi syndrome; B. ... X-linked hypophosphatemia This page was last edited on 27 July 2013, at 21:10 (UTC). Text ...
Heterozygous females have an X-chromosome from each parent; one with a mutated gene and one with a functional copy of the same gene. When the mutated chromosome is randomly inactivated in order to maintain the copy number, presence of the functional copy results in a normal phenotype. [5] Males only have one copy of any gene on the X-chromosome ...
Pseudodominance is the situation in which the inheritance of a recessive trait mimics a dominant pattern. [1]Normally, two recessive alleles need to be inherited (one from each parent) for the recessive trait to be expressed but recessive merely means that the trait is only expressed in the absence of the dominant alleles.