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Lisdexamfetamine, sold under the brand names Vyvanse and Elvanse among others, is a stimulant medication that is used to treat attention deficit hyperactivity disorder (ADHD) in children and adults and for moderate-to-severe binge eating disorder in adults. [16]
The drugs include Adderall, Vyvanse and generic amphetamines, such as dextroamphetamine. The link between amphetamines and psychosis isn’t new. Amphetamines increase levels of dopamine in the brain.
Drugs in the class of amphetamines, or substituted amphetamines, are known to induce "amphetamine psychosis" typically when chronically abused or used in high doses. [8] In an Australian study of 309 active methamphetamine users, 18% had experienced a clinical level psychosis in the past year. [9]
[20] [64] The body metabolizes methamphetamine into amphetamine (in addition to less active metabolites). A quarter of methamphetamine will ultimately become amphetamine. [65] After comparing only the common ground between dextroamphetamine and dextromethamphetamine, the latter is said to be the stronger stimulant. [20] [66]
Most stimulants are amphetamine-based (Adderall, Vyvanse) or methylphenidate-based (Concerta, Ritalin), and come in immediate-release (short-acting) or extended-release (long-acting) formulations.
The Drug Enforcement Administration is increasing the production limit of Vyvanse and its generic equivalents by about 24% to address the ongoing global shortage of ADHD medications.
Vyvanse (lisdexamfetamine) – a pro-drug stimulant used to treat attention deficit hyperactivity disorder and binge eating disorder; Vyvanse is converted into Dexedrine in vivo; Viibryd – an antidepressant of the serotonin modulator and stimulators class; Vivactil (protriptyline) an antidepressant also used in the treatment of nerve pain
Harm Reduction International reports: "imposition of one death sentence for drug use and trafficking of amphetamines and cannabis resin in June 2022. This is the first drug-related death sentence noted by a reputable source in 11 years". [1] [31]