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It is a first-generation antihistamine and works by blocking the histamine H 1 receptor. [2] Common side effects include sleepiness, restlessness, and weakness. Other side effects may include dry mouth and wheeziness. [2] Chlorpheniramine was patented in 1948 and came into medical use in 1949. [3] It is available as a generic medication and ...
Pheniramine (trade name Avil among others) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.It has relatively strong sedative effects, and may sometimes be used off-label as an over-the-counter sleeping pill in a similar manner to other sedating antihistamines such as diphenhydramine.
Coricidin, Coricidin 'D' (decongestant), or Coricidin HBP (for high blood pressure), is the name of an over-the-counter cough and cold drug containing dextromethorphan (a cough suppressant) and chlorpheniramine maleate (an antihistamine). [1] Introduced by Schering-Plough in 1949 as one of the first antihistamines, it is now owned by Bayer.
However, many side effects are common. Corex is known to cause short term memory loss, sleeplessness, tremors and spasms. Muscular pains and dehydration are other common side-effects. Long term abuse leads to serious kidney damage or constipation. Corex has a high sugar content, and may be unsuitable for acute diabetic patients.
Tripelennamine, sold under the brand name Pyribenzamine by Novartis, is a drug that is used as an antipruritic and first-generation antihistamine.It can be used in the treatment of asthma, hay fever, rhinitis, and urticaria, but is now less common as it has been replaced by newer antihistamines.
Coricidin, Coricidin D, or Coricidin HBP, is the brand name of a combination of dextromethorphan and chlorpheniramine maleate (an antihistamine). [citation needed] Varieties may also contain acetaminophen and guaifenesin. [citation needed] Codral is a brand name manufactured by Johnson & Johnson and sold primarily in Australia and New Zealand ...
Both products contained chlorpheniramine maleate (an antihistamine) and phenylpropanolamine hydrochloride (a decongestant) but differed in their doses. Both products contained 75 mg of phenylpropanolamine hydrochloride, but Cold Capsule IV contained 12 mg chlorpheniramine maleate while Cold Capsule V had 8 mg [ 1 ] .
Dexchlorpheniramine is an antihistamine, or an antagonist of the histamine H 1 receptor. A study found that dexchlorpheniramine had a K i value of 20 to 30 μM for the muscarinic acetylcholine receptors using rat brain tissue. [4]