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A medical triad is a group of three signs or symptoms, the result of injury to three organs, which characterise a specific medical condition. The appearance of all three signs conjoined together in another patient, points to that the patient has the same medical condition, or diagnosis.
An example of a triad is Meltzer's triad presenting purpura a rash, arthralgia painful joints, and myalgia painful and weak muscles. Meltzer's triad indicates the condition cryoglobulinemia. Huntington's disease is a neurodegenerative disease that is characterized by a triad of motor, cognitive, and psychiatric signs and symptoms. [31]
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In mammals, triads are typically located at the A-I junction; [1] that is, the junction between the A and I bands of the sarcomere, which is the smallest unit of a muscle fiber. Triads form the anatomical basis of excitation-contraction coupling , whereby a stimulus excites the muscle and causes it to contract.
The trauma triad of death is a medical term describing the combination of hypothermia, acidosis, and coagulopathy. [1] This combination is commonly seen in patients who have sustained severe traumatic injuries and results in a significant rise in the mortality rate . [ 2 ]
Charcot's cholangitis triad is the combination of jaundice; fever, usually with rigors; and right upper quadrant abdominal pain. It occurs as a result of ascending cholangitis (an infection of the bile duct in the liver). When the presentation also includes low blood pressure and mental status changes, it is known as Reynolds' pentad. [1]
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