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Suvorexant is used for the treatment of insomnia, characterized by difficulties with sleep onset and/or sleep maintenance, in adults. [2] [6] At a dose of 15 to 20 mg and in terms of treatment–placebo difference, it reduces time to sleep onset by up to 10 minutes, reduces time awake after sleep onset by about 15 to 30 minutes, and increases total sleep time by about 10 to 20 minutes. [2]
Middle-of-the-night insomnia, or "sleep maintenance insomnia", also called terminal insomnia in contrast with "initial insomnia", is characterized by having difficulty returning to sleep after waking up during the night or very early in the morning. Initial or "sleep-onset" insomnia consists of having difficulty falling asleep at the beginning ...
Orexin receptor antagonists are a more recently introduced class of sleep medications and include suvorexant, lemborexant, and daridorexant, all of which are FDA-approved for treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance.
Called sleep-maintenance insomnia, it affects more women than men. You typically start to worry about getting back to sleep at a reasonable time, and you also may have thoughts that become more ...
Ramelteon, sold under the brand name Rozerem among others, is a melatonin agonist medication which is used in the treatment of insomnia. [3] [5] It is indicated specifically for the treatment of insomnia characterized by difficulties with sleep onset. [3] It reduces the time taken to fall asleep, but the degree of clinical benefit is small. [6]
Lemborexant, sold under the brand name Dayvigo, is an orexin antagonist medication which is used in the treatment of insomnia. [3] [8] It is indicated specifically for the treatment of insomnia characterized by difficulties with sleep onset and/or maintenance in adults. [3] [8] The medication is taken by mouth. [3] [8]
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