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The short-term effects of cannabis can be altered if it has been laced with opioid drugs such as heroin or fentanyl. [160] The added drugs are meant to enhance the psychoactive properties, add to its weight, and increase profitability, despite the increased danger of overdose. [161] [d]
The subjective effects of sativas and indicas are said to differ, but the ratio of tetrahydrocannabinol (THC) to cannabidiol (CBD) in most named drug varieties of both types is similar (averaging about 200:1). Unlike most commercially developed strains, indica landraces exhibit plants with varying THC/CBD ratios. [7]
Cannabis plants vary widely, with different strains producing dynamic balances of cannabinoids (THC, CBD, etc.) and yielding markedly different effects. Popular strains are often hybrids of C. sativa and C. indica. The medicinal effects of cannabis are widely studied, and are active topics of research both at universities and private research ...
The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
Cannabis has many different names, including more than 1,200 slang terms, and more than 2,300 names for individual strains. [1] Additionally, there are many names to describe the state of being under the influence of the substance. [2] This list is not exhaustive; it includes well-attested names.
Also, the advent of the hypodermic syringe allowed these drugs to be injected for immediate effect, in contrast to cannabis which is not water-soluble and therefore cannot be injected. [ 87 ] In the United States, the medical use of cannabis further declined with the passage of the Marihuana Tax Act of 1937 , which imposed new regulations and ...
[13] [14] In 2018, the United States Food and Drug Administration warned of significant health risks from synthetic cannabinoid products that contain the rat poison brodifacoum, which is added because it is thought to extend the duration of the drugs' effects. [15] Severe illnesses and death have resulted from this contamination. [15]
In Phase III trials, the most common adverse effects were dizziness, drowsiness and disorientation; 12% of subjects stopped taking the drug because of the side effects. [57] Dronabinol (brand names Marinol and Syndros) is a delta-9-THC containing drug for treating HIV/AIDS-induced anorexia and chemotherapy-induced nausea and vomiting. [58]