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  2. Evolutionary biology - Wikipedia

    en.wikipedia.org/wiki/Evolutionary_biology

    Evolutionary biology is the subfield of biology that studies the evolutionary processes (natural selection, common descent, speciation) that produced the diversity of life on Earth. It is also defined as the study of the history of life forms on Earth. Evolution holds that all species are related and gradually change over generations. [1]

  3. Genetic variation - Wikipedia

    en.wikipedia.org/wiki/Genetic_variation

    Genetic variation is the difference in DNA among individuals [1] or the differences between populations among the same species. [2] The multiple sources of genetic variation include mutation and genetic recombination. [3] Mutations are the ultimate sources of genetic variation, but other mechanisms, such as genetic drift, contribute to it, as ...

  4. Population genetics - Wikipedia

    en.wikipedia.org/wiki/Population_genetics

    This process is often characterized by a description of the starting and ending states, or the kind of change that has happened at the level of DNA (e.g,. a T-to-C mutation, a 1-bp deletion), of genes or proteins (e.g., a null mutation, a loss-of-function mutation), or at a higher phenotypic level (e.g., red-eye mutation).

  5. Neutral theory of molecular evolution - Wikipedia

    en.wikipedia.org/wiki/Neutral_theory_of...

    A coherent theory of neutral evolution was first proposed by Motoo Kimura in 1968 [9] and by King and Jukes independently in 1969. [10] Kimura initially focused on differences among species; King and Jukes focused on differences within species. Many molecular biologists and population geneticists also contributed to the development of the ...

  6. Mutation - Wikipedia

    en.wikipedia.org/wiki/Mutation

    The typical human genome also contains 40,000 to 200,000 rare variants observed in less than 0.5% of the population that can only have occurred from at least one de novo germline mutation in the history of human evolution. [142] De novo mutations have also been researched as playing a crucial role in the persistence of genetic disease in humans.

  7. Molecular evolution - Wikipedia

    en.wikipedia.org/wiki/Molecular_evolution

    Molecular evolution describes how inherited DNA and/or RNA change over evolutionary time, and the consequences of this for proteins and other components of cells and organisms. Molecular evolution is the basis of phylogenetic approaches to describing the tree of life. Molecular evolution overlaps with population genetics, especially on shorter ...

  8. Single-nucleotide polymorphism - Wikipedia

    en.wikipedia.org/wiki/Single-nucleotide_polymorphism

    The OMIM database describes the association between polymorphisms and diseases (e.g., gives diseases in text form) dbSAP – single amino-acid polymorphism database for protein variation detection [59] The Human Gene Mutation Database provides gene mutations causing or associated with human inherited diseases and functional SNPs

  9. Glossary of genetics and evolutionary biology - Wikipedia

    en.wikipedia.org/wiki/Glossary_of_genetics_and...

    See reticulate evolution. neutral mutation 1. Any mutation of a nucleic acid sequence that is neither beneficial nor detrimental to the ability of an organism to survive and reproduce. 2. Any mutation for which natural selection does not affect the spread of the mutation within a population. nexus hypothesis

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