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Apolipoprotein B is the primary apolipoprotein of chylomicrons, VLDL, Lp(a), IDL, and LDL particles (LDL—commonly known as "bad cholesterol" when in reference to both heart disease and vascular disease in general), which is responsible for carrying fat molecules (), including cholesterol, around the body to all cells within all tissues.
ApoB is an integral apoprotein whereas the others are peripheral apoproteins. Apolipoprotein synthesis such as ApoA4 in hypothalamus involves in the integration of signals for regulation of food intake [ 5 ] which is regulated by vagal nerve and cholecystokinin .
On the cardiovascular front, psyllium husk powder may be beneficial as well. “Psyllium husk may help lower cholesterol and other substances that promote heart disease.
4018 n/a Ensembl ENSG00000198670 n/a UniProt P08519 n/a RefSeq (mRNA) NM_005577 n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 6: 160.53 – 160.66 Mb n/a PubMed search n/a Wikidata View/Edit Human Lipoprotein(a) is a low-density lipoprotein variant containing a protein called apolipoprotein(a). Genetic and epidemiological studies have identified lipoprotein(a) as a risk factor for ...
LDL contains apolipoprotein B (apoB), which allows LDL to bind to different tissues, such as the artery wall if the glycocalyx has been damaged by high blood sugar levels. [8] If oxidised, the LDL can become trapped in the proteoglycans, preventing its removal by HDL cholesterol efflux. [ 8 ]
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Apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 also known as C->U-editing enzyme APOBEC-1 is a protein that in humans is encoded by the APOBEC1 gene. [ 5 ] This gene encodes a member of the APOBEC protein family and the cytidine deaminase enzyme family.