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Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumour (PEComa).
In this article, I describe rapamycin and why many people have started taking it. I will explain, with my doctor’s consent, why I started and stopped taking the “anti-aging” drug rapamycin ...
Johnson had been taking rapamycin for five years and stopped last September. “I take this because there’s potentially some longevity benefits,” the 47-year-old explained in his documentary.
Although a prospective cohort study of middle-aged women indicated that some flavonoid-rich foods are associated with a reduction in all-cause mortality, frequent grapefruit consumption was associated with a small increase in all-cause mortality, possibly because of the clinically significant drug interactions of the non-flavonoid components. [8]
mTOR inhibitors are a class of drugs used to treat several human diseases, including cancer, autoimmune diseases, and neurodegeneration. They function by inhibiting the mammalian target of rapamycin (mTOR) (also known as the mechanistic target of rapamycin), which is a serine/threonine-specific protein kinase that belongs to the family of phosphatidylinositol-3 kinase (PI3K) related kinases ...
Weight loss is a famous side effect of Ozempic, the Type 2 diabetes drug, but patients often find they must avoid certain foods on the medication. It’s a similar story with Wegovy, the form of ...
Erythromycin.The macrolide ring is the lactone (cyclic ester) at upper left. Clarithromycin Roxithromycin. Macrolides are a class of mostly natural products with a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached.
Meanwhile, the Dog Aging Project, a longitudinal study investigating the aging process in dogs, is analyzing the effects of rapamycin – a drug that’s sometimes used in cancer therapies and to ...