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The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...
The blood vessels in the dermis provide nourishment and waste removal from its own cells as well as from the stratum basale of the epidermis. The dermis is structurally divided into two areas: a superficial area adjacent to the epidermis, called the papillary region , and a deep thicker area known as the reticular region .
The blood vessels in the dermis provide nourishment and waste removal from its own cells as well as for the epidermis. Dermis and subcutaneous tissues are thought to contain germinative cells involved in formation of horns, osteoderm, and other extra-skeletal apparatus in mammals.
The reticular layer is the deep layer of the dermis and consists of the dense irregular connective tissue. These layers serve to give elasticity to the integument, allowing stretching and conferring flexibility, while also resisting distortions, wrinkling, and sagging. [3] The dermal layer provides a site for the endings of blood vessels and ...
The dermis contains two vascular networks that run parallel to the skin surface—one superficial and one deep plexus—which are connected by vertical communicating vessels. [8] [11] The function of blood vessels within the dermis is fourfold: to supply nutrition, to regulate temperature, to modulate inflammation, and to participate in wound ...
Blood vessels soon grow into the dermis, restoring circulation. If the injury is very minor, the epithelial cells eventually restore the epidermis once the dermis has been regenerated. In major injuries, the repair mechanisms are unable to restore the skin to its original condition.
They also occur in the papillary dermis, particularly around blood vessels, [4] as well as in the mucosa of the mouth, foreskin, and vaginal epithelium. [5] They can be found in other tissues, such as lymph nodes , particularly in association with the condition Langerhans cell histiocytosis (LCH).
A glomus body (or glomus organ; plural glomera) is a component of the dermis layer of the skin, involved in body temperature regulation. [1] [2] The glomus body is a small arteriovenous anastomosis surrounded by a capsule of connective tissue. Glomera are most numerous in the fingers and toes.