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Rotaviruses, noroviruses, adenoviruses, and astroviruses are known to cause viral gastroenteritis. [26] Rotavirus is the most common cause of gastroenteritis in children, [25] and produces similar rates in both the developed and developing world. [20] Viruses cause about 70% of episodes of infectious diarrhea in the pediatric age group. [13]
NSP4 is a viral enterotoxin that induces diarrhoea and was the first viral enterotoxin discovered. [56] It is a viroporin that elevates cytosolic Ca 2+ in mammalian cells. [57] NSP5 is encoded by genome segment 11 of rotavirus A. In virus-infected cells NSP5 accumulates in the viroplasm. [58]
Norovirus, also known as Norwalk virus and sometimes referred to as the winter vomiting disease, is the most common cause of gastroenteritis. [1] [6] Infection is characterized by non-bloody diarrhea, vomiting, and stomach pain.
Gastroenteritis can be caused by viral, bacterial, or parasitic infections. Common routes of infection include: Food; Contaminated water; Contact with an infected person; Unwashed hands [2] Fifty to seventy percent of cases of gastroenteritis in adults are caused by noroviruses (genus Norovirus, family Caliciviridae). This virus is highly ...
Infectious diarrhea is frequently referred to as gastroenteritis. [30] Norovirus is the most common cause of viral diarrhea in adults, [31] but rotavirus is the most common cause in children under five years old. [32] Adenovirus types 40 and 41, [33] and astroviruses cause a significant number of infections. [34]
Human astroviruses are associated with gastroenteritis in children and immunocompromised adults. [32] 2–8% of acute non-bacterial gastroenteritis in children is associated with human astrovirus. These viral particles are usually detected in epithelial cells of the duodenum. [4]
Sapovirus is a genetically diverse genus of single-stranded positive-sense RNA, non-enveloped viruses within the family Caliciviridae. [1] [2] Together with norovirus, sapoviruses are the most common cause of acute gastroenteritis (commonly called the "stomach flu" although it is not related to influenza) in humans and animals.
The virus can live on hard surfaces for several weeks and as few as 18 viral particles (virons) are enough to make a person sick (compared to 1,000 for the common flu). Common home cleaning agents do not eliminate the virus and it is only removed from a person's hands by repeatedly washing them.