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  2. Digestive enzyme - Wikipedia

    en.wikipedia.org/wiki/Digestive_enzyme

    The enzymes that are secreted in the stomach are gastric enzymes. The stomach plays a major role in digestion, both in a mechanical sense by mixing and crushing the food, and also in an enzymatic sense, by digesting it. The following are enzymes produced by the stomach and their respective function: Pepsin is the main gastric enzyme.

  3. Stomach - Wikipedia

    en.wikipedia.org/wiki/Stomach

    The breakdown of protein begins in the stomach through the actions of hydrochloric acid, and the enzyme pepsin. The stomach can also produce gastric lipase, which can help digesting fat. The contents of the stomach are completely emptied into the duodenum within two to four hours after the meal is eaten.

  4. Gastrointestinal physiology - Wikipedia

    en.wikipedia.org/wiki/Gastrointestinal_physiology

    The arrangement of these proteins on the apical and basolateral sides of the epithelium determines the net movement of ions and water in the tract. H + and Cl − are secreted by the parietal cells into the lumen of the stomach creating acidic conditions with a low pH of 1. H + is pumped into the stomach by exchanging it with K +.

  5. Intrinsic factor - Wikipedia

    en.wikipedia.org/wiki/Intrinsic_factor

    Intrinsic factor (IF), cobalamin binding intrinsic factor, [5] also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells (in humans) or chief cells (in rodents) of the stomach. It is necessary for the absorption of vitamin B 12 later on in the distal ileum of the small intestine. [6]

  6. Human digestive system - Wikipedia

    en.wikipedia.org/wiki/Human_digestive_system

    A peptide hormone, gastrin, produced by G cells in the gastric glands, stimulates the production of gastric juice which activates the digestive enzymes. Pepsinogen is a precursor enzyme produced by the gastric chief cells, and gastric acid activates this to the enzyme pepsin which begins the digestion of proteins. As these two chemicals would ...

  7. Enzyme - Wikipedia

    en.wikipedia.org/wiki/Enzyme

    In 1926, James B. Sumner showed that the enzyme urease was a pure protein and crystallized it; he did likewise for the enzyme catalase in 1937. The conclusion that pure proteins can be enzymes was definitively demonstrated by John Howard Northrop and Wendell Meredith Stanley, who worked on the digestive enzymes pepsin (1930), trypsin and ...

  8. Pepsin - Wikipedia

    en.wikipedia.org/wiki/Pepsin

    Pepsin / ˈ p ɛ p s ɪ n / is an endopeptidase that breaks down proteins into smaller peptides and amino acids. It is one of the main digestive enzymes in the digestive systems of humans and many other animals, where it helps digest the proteins in food. Pepsin is an aspartic protease, using a catalytic aspartate in its active site. [2]

  9. Gastric lipase - Wikipedia

    en.wikipedia.org/wiki/Gastric_lipase

    Fatty acids and diacylglycerols are produced from this reaction. The long chain free fatty acids have the ability to prevent gastric lipase from hydrolyzing more triglycerides. In this case, gastric acid will be responsible for less than 30% of lipid hydrolysis. [5] These enzymes are found in the cytoplasm and cell membranes of gastric cells.