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  2. Splenectomy - Wikipedia

    en.wikipedia.org/wiki/Splenectomy

    An increase in blood leukocytes can occur following a splenectomy. [9] The post-splenectomy platelet count may rise to abnormally high levels (thrombocytosis), leading to an increased risk of potentially fatal clot formation. Mild thrombocytosis may be observed after a splenectomy due to the lack of sequestering and destruction of platelets ...

  3. Spleen - Wikipedia

    en.wikipedia.org/wiki/Spleen

    Splenosis is a condition where displaced pieces of splenic tissue (often following trauma or splenectomy) autotransplant in the abdominal cavity as accessory spleens. [28] Polysplenia is a congenital disease manifested by multiple small accessory spleens, [29] rather than a single, full-sized, normal spleen.

  4. White blood cell - Wikipedia

    en.wikipedia.org/wiki/White_blood_cell

    White blood cells (scientific name leukocytes), also called immune cells or immunocytes, are cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders. White blood cells are generally larger than red blood cells.

  5. Pelger–Huët anomaly - Wikipedia

    en.wikipedia.org/wiki/Pelger–Huët_anomaly

    Is a benign dominantly inherited defect of terminal neutrophil differentiation as a result of mutations in the lamin B receptor gene. The characteristic leukocyte appearance was first reported in 1928 by Karel Pelger (1885-1931), a Dutch Hematologist, who described leukocytes with dumbbell-shaped bilobed nuclei, a reduced number of nuclear segments, and coarse clumping of the nuclear chromatin.

  6. Splenomegaly - Wikipedia

    en.wikipedia.org/wiki/Splenomegaly

    Splenomegaly is an enlargement of the spleen. [1] The spleen usually lies in the left upper quadrant (LUQ) of the human abdomen.Splenomegaly is one of the four cardinal signs of hypersplenism which include: some reduction in number of circulating blood cells affecting granulocytes, erythrocytes or platelets in any combination; a compensatory proliferative response in the bone marrow; and the ...

  7. White blood cell differential - Wikipedia

    en.wikipedia.org/wiki/White_blood_cell_differential

    A white blood cell differential is a medical laboratory test that provides information about the types and amounts of white blood cells in a person's blood. The test, which is usually ordered as part of a complete blood count (CBC), measures the amounts of the five normal white blood cell types – neutrophils, lymphocytes, monocytes, eosinophils and basophils – as well as abnormal cell ...

  8. Asplenia - Wikipedia

    en.wikipedia.org/wiki/Asplenia

    Acquired asplenia occurs for several reasons: . Following splenectomy due to splenic rupture from trauma or because of tumor; After splenectomy with the goal of interfering with splenic function, as a treatment for diseases (e.g. idiopathic thrombocytopenic purpura, thalassemia, spherocytosis), in which the spleen's usual activity exacerbates the disease

  9. Splenocyte - Wikipedia

    en.wikipedia.org/wiki/Splenocyte

    Splenocytes are spleen cells and consist of leukocytes like B and T cells, dendritic cells, and macrophages. [2] The spleen is split into red and white pulp regions with the marginal zone separating the two areas. The red pulp is involved with filtering blood and recycling iron, while the white pulp is involved in the immune response. [2]