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  2. Route of administration - Wikipedia

    en.wikipedia.org/wiki/Route_of_administration

    The parenteral route is any route that is not enteral (par-+ enteral). Parenteral administration can be performed by injection, that is, using a needle (usually a hypodermic needle) and a syringe, [16] or by the insertion of an indwelling catheter. Locations of application of parenteral administration include: Central nervous system:

  3. Neonatal withdrawal - Wikipedia

    en.wikipedia.org/wiki/Neonatal_withdrawal

    Substance examples of long term effects as follows: Alcohol exposure has shown it could lead to poor growth. Tobacco exposure can make it more likely to get obese. Alcohol, nicotine, and opiate exposure have shown to lead to attention deficits. Nicotine and alcohol exposure affect learning and memory.

  4. Systemic administration - Wikipedia

    en.wikipedia.org/wiki/Systemic_administration

    Administration can take place via enteral administration (absorption of the drug through the gastrointestinal tract) [2] or parenteral administration (generally injection, infusion, or implantation). [3] [4] Contrast with topical administration where the effect is generally local. [4]

  5. Area under the curve (pharmacokinetics) - Wikipedia

    en.wikipedia.org/wiki/Area_under_the_curve...

    The AUC (from zero to infinity) represents the total drug exposure across time. AUC is a useful metric when trying to determine whether two formulations of the same dose (for example a capsule and a tablet) result in equal amounts of tissue or plasma exposure. Another use is in the therapeutic drug monitoring of drugs with a narrow therapeutic ...

  6. FDA takes first step to protect children from medications ...

    www.aol.com/news/fda-takes-first-step-protect...

    Children will get into anything, and children will especially get into anything that tastes or looks like candy,” said Dr. Theresa Michele, who leads the FDA’s office of nonprescription drugs.

  7. Injection (medicine) - Wikipedia

    en.wikipedia.org/wiki/Injection_(medicine)

    This is termed parenteral nutrition and may provide all or only part of a person's nutritional requirements. Parenteral nutrition may be pre-mixed or customized for a person's specific needs. [6] Intravenous injections may also be used for recreational drugs when a rapid onset of effects is desired. [7] [8]

  8. Bioavailability - Wikipedia

    en.wikipedia.org/wiki/Bioavailability

    It is the fraction of exposure to a drug (AUC) through non-intravenous administration compared with the corresponding intravenous administration of the same drug. [17] The comparison must be dose normalized (e.g., account for different doses or varying weights of the subjects); consequently, the amount absorbed is corrected by dividing the ...

  9. Fentanyl in other drugs: Why do drug dealers mix them? What ...

    www.aol.com/fentanyl-other-drugs-why-drug...

    In addition to the added potency, the drug has a “low cost,” which leads drug dealers to mix fentanyl with drugs like “heroin, methamphetamine and cocaine, increasing the likelihood of a ...