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  2. Silicone gel sheeting - Wikipedia

    en.wikipedia.org/wiki/Silicone_gel_sheeting

    The exact mechanism of action of silicone gel sheeting has not been fully studied. Currently, many proposed mechanisms explain the efficacy of such treatment, including the occlusion and hydration effect, increased body surface temperature, polarized electric charge, immunological effects, etc. [9] The occlusion and hydration effect is the most studied mechanism of action.

  3. Medical grade silicone - Wikipedia

    en.wikipedia.org/wiki/Medical_grade_silicone

    Medical grade silicones are silicones tested for biocompatibility and are appropriate to be used for medical applications. [1] In the United States, the Food and Drug Administration (FDA) Center for Devices and Radiological Health (CDRH) regulates devices implanted into the body. It does not regulate materials other than certain dental materials.

  4. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    Toxic Dose the dose at which toxicity occurs in 50% of cases. LD Lethal Dose the dose at which death occurs in 50% of cases. [6]: 73 [7] [8] TI Therapeutic Index a quantitative measurement of the relative safety of a drug by comparison of the amount of a therapeutic agent that causes toxicity to the amount that causes the therapeutic effect [1]

  5. IARC group 1 - Wikipedia

    en.wikipedia.org/wiki/IARC_group_1

    IARC group 1 Carcinogens are substances, chemical mixtures, and exposure circumstances which have been classified as carcinogenic to humans by the International Agency for Research on Cancer (IARC). [1] This category is used when there is sufficient evidence of carcinogenicity in humans.

  6. Polyvinylpyrrolidone - Wikipedia

    en.wikipedia.org/wiki/Polyvinylpyrrolidone

    as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating as a thickening agent in tooth whitening gels [ 15 ] as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms ( syrups , soft gelatine capsules ) and as an inhibitor of recrystallisation [ 16 ]

  7. Acute toxicity - Wikipedia

    en.wikipedia.org/wiki/Acute_toxicity

    Acute toxicity describes the adverse effects of a substance that result either from a single exposure [1] or from multiple exposures in a short period of time (usually less than 24 hours). [ 2 ] To be described as acute toxicity, the adverse effects should occur within 14 days of the administration of the substance.

  8. Human equivalent - Wikipedia

    en.wikipedia.org/wiki/Human_equivalent

    Animal models are used to learn more about a disease, its diagnosis and its treatment, with animal models predicting human toxicity in up to 71% of cases. [1] The human equivalent dose (HED) or human equivalent concentration (HEC) is the quantity of a chemical that, when administered to humans, produces an effect equal to that produced in test animals by a smaller dose. [2]

  9. Carboxymethyl cellulose - Wikipedia

    en.wikipedia.org/wiki/Carboxymethyl_cellulose

    Carboxymethyl cellulose (CMC) is used in applications ranging from food production to medical treatments. [9] It is commonly used as a viscosity modifier or thickener and to stabilize emulsions in both food and non-food products.

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