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Rosalind Franklin joined King's College London in January 1951 to work on the crystallography of DNA. By the end of that year, she established two important facts: one is that phosphate groups, which are the molecular backbone for the nucleotide chains, lie on the outside (it was a general consensus at the time that they were at the inside); and the other is that DNA exists in two forms, a ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 15 February 2025. British X-ray crystallographer (1920–1958) This article is about the chemist. For the Mars rover named after her, see Rosalind Franklin (rover). Rosalind Franklin Franklin with a microscope in 1955 Born Rosalind Elsie Franklin (1920-07-25) 25 July 1920 Notting Hill, London, England ...
The double-helix model of DNA structure was first published in the journal Nature by James Watson and Francis Crick in 1953, [6] (X,Y,Z coordinates in 1954 [7]) based on the work of Rosalind Franklin and her student Raymond Gosling, who took the crucial X-ray diffraction image of DNA labeled as "Photo 51", [8] [9] and Maurice Wilkins, Alexander Stokes, and Herbert Wilson, [10] and base-pairing ...
Photo 51 is an X-ray based fiber diffraction image of a paracrystalline gel composed of DNA fiber [1] taken by Raymond Gosling, [2] [3] a postgraduate student working under the supervision of Maurice Wilkins and Rosalind Franklin at King's College London, while working in Sir John Randall's group.
Nuclear DNA is a nucleic acid, a polymeric biomolecule or biopolymer, found in the nucleus of eukaryotic cells.Its structure is a double helix, with two strands wound around each other, a structure first described by Francis Crick and James D. Watson (1953) using data collected by Rosalind Franklin.
Rosalind Franklin: The Dark Lady of DNA is a biography of Rosalind Franklin, a scientist whose work helped discover the structure of DNA. [1] [2] It was written by Brenda Maddox and published by HarperCollins in October 2002. [3] A play based in part on the book, Photograph 51 written by Anna Ziegler, was staged in London in 2015 starring ...
1952: an X-ray diffraction image of DNA was taken by Raymond Gosling in May 1952, a student supervised by Rosalind Franklin. [30] 1953: DNA structure is resolved to be a double helix by James Watson, Francis Crick and Maurice Wilkins. [31] 1955: Alexander R. Todd determined the chemical makeup of nitrogenous bases.
This showed that specific genes code for specific proteins, leading to the "one gene, one enzyme" hypothesis. [23] Oswald Avery, Colin Munro MacLeod, and Maclyn McCarty showed in 1944 that DNA holds the gene's information. [24] In 1952, Rosalind Franklin and Raymond Gosling produced a strikingly clear x-ray diffraction pattern indicating a ...