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Saliva testing or Salivaomics is a diagnostic technique ... Repeated exposure to initially stressful stimuli has been found to result in a leveling off of cortisol in ...
[2] [3] Dexamethasone should be used as the corticosteroid of choice in these cases as it is the only corticosteroid that will not affect diagnostic test results. [2] [29] To confirm inappropriately low cortisol secretion, testing can include baseline morning cortisol level in the blood or morning cortisol level in the saliva. [2]
Test results should, therefore, always be interpreted using the reference range from the laboratory that produced the result. [ 57 ] [ 58 ] [ 59 ] An individual's cortisol levels can be detected in blood, serum, urine, saliva, and sweat.
Immediately after the test is a debriefing, in which the participant is told that the purpose of the test was to create stress, and that the results are in no way a reflection on his or her personal abilities. Saliva and blood samples continue to be collected after the stress induction period has ended. [8]
In the alcoholic patient with pseudo-Cushing's, admission to hospital (and avoidance of alcohol) will result in normal midnight cortisol levels within five days, excluding Cushing's [6] Another cause for Cushing's syndrome is adrenocortical carcinoma. This is a rare form of cancer with an incidence of 1-2 per million people annually.
Over 40 studies that used CPT testing in various formats were analyzed to draw this conclusion. The resulting recommendation is that the use of a Continuous Performance Test would be a valuable way to screen for the disorder, the results of which could then be used as a precursor for a patient entering preventative intervention programs. [16]