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Maternal to zygotic transition (MZT), also known as embryonic genome activation, is the stage in embryonic development during which development comes under the exclusive control of the zygotic genome rather than the maternal (egg) genome. The egg contains stored maternal genetic material mRNA which controls embryo development until the onset of ...
The embryo is joined to the trophoblastic shell by a narrow connecting stalk that develops into the umbilical cord to attach the placenta to the embryo. [ 11 ] [ 15 ] Arteries in the decidua are remodelled to increase the maternal blood flow into the intervillous spaces of the placenta, allowing gas exchange and the transfer of nutrients to the ...
The zygote is the earliest developmental stage. In humans and most other anisogamous organisms, a zygote is formed when an egg cell and sperm cell come together to create a new unique organism. The formation of a totipotent zygote with the potential to produce a whole organism depends on epigenetic reprogramming.
Fertilization was not understood in antiquity. Hippocrates believed that the embryo was the product of male semen and a female factor. Aristotle held that only male semen gave rise to an embryo, while the female only provided a place for the embryo to develop, [5] a concept he acquired from the preformationist Pythagoras.
Fertilization of the ovum to form a new human organism, the human zygote. (day 1 of fertilization [1]) The zygote undergoes mitotic cellular divisions, but does not increase in size. This mitosis is also known as cleavage. A hollow cavity forms marking the blastocyst stage. (day 1.5–3 of fertilization. [1])
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The ova, which are the female sex cells, are much larger than the spermatozoon and are normally formed within the ovaries of the female fetus before birth. They are mostly fixed in location within the ovary until their transit to the uterus, and contain nutrients for the later zygote and embryo .
Fertilization is the fusing of the gametes; a sperm cell and an ovum (egg cell) fuse to form a single-cell zygote.This is the beginning of the diploid phase of the human life cycle after two genetically unique haploid cells created via meiosis and chromosomal translocation combine their DNA and begin to develop into a multi-cellular organism.
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