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A sterile version is used for making solutions that will be given by injection. [2] Before such use other substances generally must be added to make the solution isotonic. [3] Isotonic solutions containing water for injection can be given by injection into a vein, muscle, or under the skin. [4]
Ultrapure water (UPW), high-purity water or highly purified water (HPW) is water that has been purified to uncommonly stringent specifications. Ultrapure water is a term commonly used in manufacturing to emphasize the fact that the water is treated to the highest levels of purity for all contaminant types, including: organic and inorganic compounds; dissolved and particulate matter; volatile ...
Another class of ultrapure water used for pharmaceutical industries is called Water-For-Inject (WFI), typically generated by multiple distillation or compressed-vaporation [check spelling] process of DI water or RO-DI water. It has a tighter bacteria requirement as 10 CFU per 100 mL, instead of the 100 CFU per mL per USP.
Saline (also known as saline solution) is a mixture of sodium chloride (salt) and water. [1] It has a number of uses in medicine including cleaning wounds, removal and storage of contact lenses, and help with dry eyes. [2] By injection into a vein, it is used to treat hypovolemia such as that from gastroenteritis and diabetic ketoacidosis.
USP establishes documentary (written) and reference (physical) standards for medicines, food ingredients, dietary supplement products, and ingredients. These standards are used by regulatory agencies and manufacturers to help to ensure that these products are of the appropriate identity, as well as strength, quality, purity, and consistency.
The USP Controlled Room Temperature is a series of United States Pharmacopeia guidelines for the storage of pharmaceuticals; [1] the relevant omnibus standard is USP 797. [2] [3] Although 100% compliance remains challenging for any given facility, [4] the larger protocol may be regarded as constituting a form of clean room [5] which is included in a suite of best practices.
A saline flush is the method of clearing intravenous lines (IVs), central lines or arterial lines of any medicine or other perishable liquids to keep the lines (tubes) and entry area clean and sterile.
USP Tincture of Iodine is defined in the U.S. National Formulary (NF) as containing in each 100 mL, 1.8 to 2.2 grams of elemental iodine, and 2.1 to 2.6 grams of sodium iodide. Alcohol is 50 mL, and the balance is purified water. This "2% free iodine" solution has 0.08 mol/L of I 2, which provides about 1 mg of free iodine per 0.05 mL drop. The ...