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A BiTE linking a T cell to a tumor cell. Like other bispecific antibodies, and unlike ordinary monoclonal antibodies, BiTEs form a link between T cells and tumor cells. This causes T cells to exert cytotoxic activity on tumor cells by producing proteins like perforin and granzymes, independently of the presence of MHC I or co-stimulatory molecules.
The buccal fat pad (also called Bichat’s fat pad, after Xavier Bichat, and the buccal pad of fat) is one of several encapsulated fat masses in the cheek. It is a deep fat pad located on either side of the face between the buccinator muscle and several more superficial muscles (including the masseter, the zygomaticus major, and the zygomaticus minor). [1]
T-cell transfer therapy: a treatment that takes T-cells from the tumor and selects or changes them in the lab to better attack cancer cells, then reintroduces them into the patient. Monoclonal antibodies: designed to bind to specific targets on cancer cells, marking cancer cells so that they will be better seen and destroyed by the immune system.
Clevenger's fissure: found in the inferior temporal lobe of the brain; Collateral fissure: found in the inferior surface of the cerebrum. Fissure of Bichat: found below the corpus callosum in the cerebellum of the brain. Lateral sulcus or Fissure of Sylvius: separates the frontal and parietal lobes of the brain from the temporal lobe.
Marie François Xavier Bichat (/ b iː ˈ ʃ ɑː /; [3] French:; 14 November 1771 – 22 July 1802) [4] was a French anatomist and pathologist, known as the father of modern histology. [ 5 ] [ a ] Although he worked without a microscope , Bichat distinguished 21 types of elementary tissues from which the organs of the human body are composed ...
Another form of targeted therapy involves the use of nanoengineered enzymes to bind to a tumor cell such that the body's natural cell degradation process can digest the cell, effectively eliminating it from the body. Targeted cancer therapies are expected to be more effective than older forms of treatments and less harmful to normal cells.
Cell therapy (also called cellular therapy, cell transplantation, or cytotherapy) is a therapy in which viable cells are injected, grafted or implanted into a patient in order to effectuate a medicinal effect, [1] for example, by transplanting T-cells capable of fighting cancer cells via cell-mediated immunity in the course of immunotherapy, or ...
Cancer treatments are a wide range of treatments available for the many different types of cancer, with each cancer type needing its own specific treatment. [1] Treatments can include surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy including small-molecule drugs or monoclonal antibodies, [2] and PARP inhibitors such as olaparib. [3]