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Multiple variants may be present simultaneously. Tuberculosis of the lip, secondary to open pulmonary TB. There is a popular misconception that tuberculosis is purely a disease of the lungs that manifests as coughing. [47] Tuberculosis may infect many organs, even though it most commonly occurs in the lungs (known as pulmonary tuberculosis). [8]
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [ 1 ] [ 2 ] First discovered in 1882 by Robert Koch , M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid .
Some individuals may be infected with the tuberculosis mycobacterium but never display symptoms. [27] Called latent tuberculosis, these cases, while uncontagious, are particularly problematic from a public health perspective, since approximately 10% of those diagnosed with latent TB will go on to develop an active (and contagious) case. [27]
Common infections that spread by airborne transmission include SARS-CoV-2; [14] measles morbillivirus, [15] chickenpox virus; [16] Mycobacterium tuberculosis, influenza virus, enterovirus, norovirus and less commonly other species of coronavirus, adenovirus, and possibly respiratory syncytial virus. [17]
"A person with TB disease may feel perfectly healthy or may only have a cough from time to time." [12] However, these symptoms do not guarantee tuberculosis, and they may not exist at all, yet the patient may still have active tuberculosis. A person with symptoms listed may have active tuberculosis, and the person should immediately see a ...
As of 2003, the enzyme-linked immunospot assay (ELISPOT) has been another blood test available in the UK that may replace the skin test for diagnosis. [20] [21] [22] T-SPOT.TB, [23] a type of ELISpot Assay, [24] counts the number of activated T lymphocytes that secrete interferon γ.
The Mycobacterium tuberculosis complex (MTC or MTBC) is a genetically related group of Mycobacterium species that can cause tuberculosis in humans or other animals. It includes: Mycobacterium tuberculosis; Mycobacterium africanum; Mycobacterium orygis [1] Mycobacterium bovis and the Bacillus Calmette–Guérin strain; Mycobacterium microti ...
An infectious disease agent can be transmitted in two ways: as horizontal disease agent transmission from one individual to another in the same generation (peers in the same age group) [3] by either direct contact (licking, touching, biting), or indirect contact through air – cough or sneeze (vectors or fomites that allow the transmission of the agent causing the disease without physical ...