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Linaclotide, (sold under the brand name Linzess in the US and Mexico, and as Constella elsewhere) [6] is a drug used to treat irritable bowel syndrome with constipation and chronic constipation with no known cause.
Sedation is the side effect people taking lorazepam most frequently report. In a group of around 3,500 people treated for anxiety, the most common side effects complained of from lorazepam were sedation (15.9%), dizziness (6.9%), weakness (4.2%), and unsteadiness (3.4%). Side effects such as sedation and unsteadiness increased with age. [61]
Improved reaction times were noted at 52 weeks in elderly patients free from benzodiazepines. This is an important function in the elderly, especially if they drive a car due to the increased risk of road traffic accidents in benzodiazepine users. [136] At the 24-week follow-up, 80% of people had successfully withdrawn from benzodiazepines.
Ironwood Pharmaceuticals Provides Fourth Quarter 2012 Investor Update Initiated Promotional Efforts for LINZESS™ (linaclotide) with Forest in December 2012; LINZESS Available to Patients in ...
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What you really need to watch out for are the more serious side effects, which may include: Eye problems, like blurred vision, retinitis pigmentosa, or vision loss. Chest pain.
However, vitamin D supplements have no effect on preventing falls or fractures in older adults, according to the U.S. Preventative Services Task Force. Vitamin D supplementation for postmenopausal ...
As plecanatide acts on receptors present on the apical side of endothelial cells lining the gastrointestinal tract it is able to impart its effect without ever entering circulation. [13] As with most orally ingested peptides, plecanatide is degraded by intestinal enzymes, and so very little of the active drug enters systemic circulation. [ 12 ]
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