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Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species. [24] It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. [25]
Botox has been shown to be especially beneficial to reducing spasticity in the gastrocnemius (calf) muscle. This therapy can improve range of motion, reduce deformity, improve response to occupational and physical therapy, and delay the need for surgery. [5] Botulinum toxin type A injections have also shown advantages for upper extremities.
Botulinum toxin (Botox) is often used to improve some symptoms of spasmodic dysphonia through weakening or paralyzing the vocal folds, thus preventing muscle spasms. [ 1 ] [ 32 ] The level of evidence for its use is currently limited; little is known about optimal dosage, frequency of injections, or exact location of injection.
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If refractive to oral agents, spasticity may be treated with intrathecal baclofen therapy (IBT) when spasticity. IBT may also be used in patients with limited tolerance to other modalities. [24] Phenol injections can be used, or botulinum toxin [24] [18] [19] [25] injections into the muscle belly, to attempt to dampen the signals between nerve ...
In 2010, more than 5.3 million people got Botox and more than 1.7 million received filler in the U.S. In 2022, 8.7 million received Botox and more than 6.2 million received filler, according to ...
Common examples of neurotoxins include lead, [7] ethanol (drinking alcohol), [8] glutamate, [9] nitric oxide, [10] botulinum toxin (e.g. Botox), [11] tetanus toxin, [12] and tetrodotoxin. [6] Some substances such as nitric oxide and glutamate are in fact essential for proper function of the body and only exert neurotoxic effects at excessive ...
Fake Botox injections may have led to the hospitalizations of two people in Illinois, the state's Public Health Department said Monday. "Illinois residents should exercise caution when considering ...
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