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The gene produces an 18 kDa protein composed of 154 amino acids. [ 7 ] [ 8 ] NDUFA6 is a subunit of the enzyme NADH dehydrogenase (ubiquinone) , the largest of the respiratory complexes. The structure is L-shaped with a long, hydrophobic transmembrane domain and a hydrophilic domain for the peripheral arm that includes all the known redox ...
The NDUFB8 protein weighs 22 kDa and is composed of 186 amino acids. [ 8 ] [ 9 ] NDUFB8 is a subunit of the enzyme NADH dehydrogenase (ubiquinone) , the largest of the respiratory complexes. The structure is L-shaped with a long, hydrophobic transmembrane domain and a hydrophilic domain for the peripheral arm that includes all the known redox ...
MT-ND2 is located in mitochondrial DNA from base pair 4,470 to 5,511. [5] The MT-ND2 gene produces a 39 kDa protein composed of 347 amino acids. [10] [11] MT-ND2 is one of seven mitochondrial genes encoding subunits of the enzyme NADH dehydrogenase (ubiquinone), together with MT-ND1, MT-ND3, MT-ND4, MT-ND4L, MT-ND5, and MT-ND6.
The NDUFB6 protein weighs 15.5 kDa and is composed of 128 amino acids. [ 9 ] [ 10 ] NDUFB6 is a subunit of the enzyme NADH dehydrogenase (ubiquinone) , the largest of the respiratory complexes. The structure is L-shaped with a long, hydrophobic transmembrane domain and a hydrophilic domain for the peripheral arm that includes all the known ...
MT-ND3 is located in human mitochondrial DNA from base pair 10,059 to 10,404. [5] The MT-ND3 gene produces a 13 kDa protein composed of 115 amino acids. [9] [10] MT-ND3 is one of seven mitochondrial genes encoding subunits of the enzyme NADH dehydrogenase (ubiquinone), together with MT-ND1, MT-ND2, MT-ND4, MT-ND4L, MT-ND5, and MT-ND6.
The MT-ND4 gene is located in human mitochondrial DNA from base pair 10,760 to 12,137. [5] [11] The MT-ND4 gene produces a 52 kDa protein composed of 459 amino acids.[12] [13] MT-ND4 is one of seven mitochondrial genes encoding subunits of the enzyme NADH dehydrogenase (ubiquinone), together with MT-ND1, MT-ND2, MT-ND3, MT-ND4L, MT-ND5, and MT-ND6.
NDUFS8 is located on the q arm of chromosome 11 in position 13.2. [7] The NDUFS8 gene produces a 23.7 kDa protein composed of 210 amino acids. [10] [11] The encoded protein, TYKY, contains two 4Fe4S ferredoxin consensus patterns which are believed to be iron-sulfur cluster N-2 binding sites. [12]
The gene produces a 12.5 kDa protein composed of 113 amino acids. [ 7 ] [ 8 ] NDUFA7 is a subunit of the enzyme NADH dehydrogenase (ubiquinone) , the largest of the respiratory complexes. The structure is L-shaped with a long, hydrophobic transmembrane domain and a hydrophilic domain for the peripheral arm that includes all the known redox ...