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Depression is a mental state of low mood and aversion to activity. [3] It affects about 3.5% of the global population, or about 280 million people worldwide, as of 2020. [4] Depression affects a person's thoughts, behavior, feelings, and sense of well-being. [5]
[13] [18] Signs of low positive affect include fatigue, loneliness, sadness, and lethargy. [13] Positive affect is important because it is a construct used in order to differentiate depression from anxiety. [1] [20] Many studies were completed to evaluate the role of positive affect in the tripartite model.
The mental status examination (MSE) is an important part of the clinical assessment process in neurological and psychiatric practice. It is a structured way of observing and describing a patient's psychological functioning at a given point in time, under the domains of appearance, attitude, behavior, mood and affect, speech, thought process, thought content, perception, cognition, insight, and ...
Family history, previous diagnosis of a mood disorder, trauma, stress or major life changes in the case of depression, physical illness or use of certain medications. Depression has been linked to major diseases such as cancer, diabetes, Parkinson's disease and heart disease, Brain structure and function in the case of bipolar disorder. [1 ...
Individuals with depression often describe a slowing of thought, an inability to concentrate and make decisions, and being easily distracted. [3] In the elderly, the decreased concentration caused by a major depressive episode may present as deficits in memory. [3] This is referred to as pseudodementia and often goes away with treatment. [3]
However, in a subset of cases sleep deprivation can, paradoxically, lead to increased energy and alertness and enhanced mood. This effect is most marked in persons with an eveningness type (so called night-owls) and people suffering from depression. For this reason it has sometimes been used as a treatment for major depressive disorder. [15] [16]