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Mild polycythemia on its own is often asymptomatic. Treatment for polycythemia varies, and typically involves treating its underlying cause. [ 6 ] Treatment of primary polycythemia (see polycythemia vera ) could involve phlebotomy , antiplatelet therapy to reduce risk of blood clots, and additional cytoreductive therapy to reduce the number of ...
In oncology, polycythemia vera (PV) is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. [1] The majority of cases [ 2 ] are caused by mutations in the JAK2 gene, most commonly resulting in a single amino acid change in its protein product from valine to phenylalanine at position 617.
Phlebotomy is the process of making a puncture in a vein, usually in the arm, with a cannula for the purpose of drawing blood. [1] The procedure itself is known as a venipuncture , which is also used for intravenous therapy .
Therapeutic phlebotomy refers to the drawing of a unit of blood in specific cases like hemochromatosis, polycythemia vera, porphyria cutanea tarda, etc., to reduce the number of red blood cells. [ 6 ] [ 7 ] The traditional medical practice of bloodletting is today considered to be a pseudoscience .
289.6 Familial polycythemia; 289.7 Methemoglobinemia; 289.8 Other specified diseases of blood and blood-forming organs 289.81 Primary hypercoagulable state; 289.82 Secondary hypercoagulable state; 289.83 Myelofibrosis; 289.84 Heparin-induced thrombocytopenia; 289.89 Other specified diseases of blood and blood-forming organs
Polycythemia vera (PV), a myeloproliferative disorder in which the bone marrow produces excessive numbers of red cells, is associated with elevated hematocrit. [citation needed] Chronic obstructive pulmonary disease (COPD) and other pulmonary conditions associated with hypoxia may elicit an increased production of red blood cells.
In the European Union, ropeginterferon alfa-2b is indicated as monotherapy in adults for the treatment of polycythemia vera without symptomatic splenomegaly. [4] In the United States it is indicated for the treatment of polycythemia vera. [2] [3] [6] Ropeginterferon alfa-2b showed promising clinical activities in the treatment of moderate COVID ...
A complete blood count (CBC), also known as a full blood count (FBC), is a set of medical laboratory tests that provide information about the cells in a person's blood.The CBC indicates the counts of white blood cells, red blood cells and platelets, the concentration of hemoglobin, and the hematocrit (the volume percentage of red blood cells).