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In oncology, polycythemia vera (PV) is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. [1] The majority of cases [ 2 ] are caused by mutations in the JAK2 gene, most commonly resulting in a single amino acid change in its protein product from valine to phenylalanine at position 617.
She was also diagnosed with a rare blood disease polycythemia vera, where the body makes too many red blood cells that thicken the blood and clots according to Mayo Clinic. To address the ...
Polycythemia vera (PCV) (a.k.a. polycythemia rubra vera (PRV)) occurs when excess red blood cells are produced as a result of an abnormality of the bone marrow. [3] Often, excess white blood cells and platelets are also produced. A hallmark of polycythemia vera is an elevated hematocrit, with Hct > 55% seen in 83% of cases. [19]
This is an incomplete list, which may never be able to satisfy certain standards for completion.. There are many conditions of or affecting the human hematologic system—the biological system that includes plasma, platelets, leukocytes, and erythrocytes, the major components of blood and the bone marrow.
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Other associated conditions include heparin-induced thrombocytopenia, catastrophic antiphospholipid syndrome, [93] paroxysmal nocturnal hemoglobinuria, [94] nephrotic syndrome, [58] chronic kidney disease, [95] polycythemia vera, essential thrombocythemia, [96] intravenous drug use, [97] and smoking. [d]
Diets rich in four different types of nutrients may help reduce iron buildup in the brain and lower the risk of cognitive decline that comes with aging, a new study suggests.
Secondary erythromelalgia can result from small fiber peripheral neuropathy of any cause, polycythemia vera, essential thrombocythemia, [1] hypercholesterolemia, mushroom or mercury poisoning, and some autoimmune disorders. Primary erythromelalgia is caused by mutation of the voltage-gated sodium channel α-subunit gene SCN9A.