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  2. Diphenhydramine - Wikipedia

    en.wikipedia.org/wiki/Diphenhydramine

    Diphenhydramine is a first-generation antihistamine used to treat several conditions including allergic symptoms and itchiness, the common cold, insomnia, motion sickness, and extrapyramidal symptoms. [19] [20] Diphenhydramine also has local anesthetic properties, and has been used as such in people allergic to common local anesthetics such as ...

  3. Antihistamine - Wikipedia

    en.wikipedia.org/wiki/Antihistamine

    Older people are more likely to experience drowsiness from antihistamine use than younger people. [1] Continuous and/or cumulative use of anticholinergic medications, including first-generation antihistamines, is associated with higher risk for cognitive decline and dementia in older people. [31] [32]

  4. Desloratadine - Wikipedia

    en.wikipedia.org/wiki/Desloratadine

    Desloratadine is a selective H 1-antihistamine which functions as an inverse agonist at the histamine H 1 receptor. [14] At very high doses, is also an antagonist at various subtypes of the muscarinic acetylcholine receptors. This effect is not relevant for the drug's action at therapeutic doses. [15]

  5. Fexofenadine - Wikipedia

    en.wikipedia.org/wiki/Fexofenadine

    Fexofenadine does not readily cross the blood–brain barrier, so is less likely to cause drowsiness in comparison to other antihistamines that readily cross that barrier (i.e., first-generation antihistamines such as diphenhydramine). In general, fexofenadine takes about an hour to take effect, though this may be affected by the choice of ...

  6. Cetirizine - Wikipedia

    en.wikipedia.org/wiki/Cetirizine

    Cetirizine is a second-generation antihistamine used to treat allergic rhinitis (hay fever), dermatitis, and urticaria (hives). [5] It is taken by mouth. [6] Effects generally begin within thirty minutes and last for about a day. [6] The degree of benefit is similar to other antihistamines such as diphenhydramine, which is a first-generation ...

  7. This Popular Cold Medicine Doesn't Work—Here's What To Buy ...

    www.aol.com/popular-cold-medicine-doesnt-heres...

    That doesn't mean you shouldn't also use pseudoephedrine in addition to nasal steroid sprays or nasal antihistamine sprays, but it’s best to limit pseudoephedrine use to a short-term period. Dr.

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