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The reward system (the mesocorticolimbic circuit) is a group of neural structures responsible for incentive salience (i.e., "wanting"; desire or craving for a reward and motivation), associative learning (primarily positive reinforcement and classical conditioning), and positively-valenced emotions, particularly ones involving pleasure as a core component (e.g., joy, euphoria and ecstasy).
Investigation of the brain reward circuitry reveals that it consists of a distributed, multi-synaptic circuit that determines both BSR and natural reward function. [1] The natural drives that motivate and shape behavior reach the reward circuitry trans-synaptically through the peripheral senses of sight, sound, taste, smell, or touch.
The mesolimbic pathway, sometimes referred to as the reward pathway, is a dopaminergic pathway in the brain. [1] The pathway connects the ventral tegmental area in the midbrain to the ventral striatum of the basal ganglia in the forebrain. The ventral striatum includes the nucleus accumbens and the olfactory tubercle. [2]
The main dopaminergic pathways of the human brain. Dopaminergic pathways (dopamine pathways, dopaminergic projections) in the human brain are involved in both physiological and behavioral processes including movement, cognition, executive functions, reward, motivation, and neuroendocrine control. [1]
Incentive salience is a cognitive process that grants a "desire" or "want" attribute, which includes a motivational component to a rewarding stimulus. [1] [2] [3] [9] Reward is the attractive and motivational property of a stimulus that induces appetitive behavior – also known as approach behavior – and consummatory behavior. [3]
One such region is the nucleus accumbens—a key part of the brain’s reward system that’s fueled by dopamine, a chemical that Wise fondly refers to as “the slutty neurotransmitter” because ...
The brain's reward system assigns it incentive salience (i.e., it is "wanted" or "desired"), [41] [42] [43] so as an addiction develops, deprivation of the drug leads to craving. In addition, stimuli associated with drug use – e.g., the sight of a syringe, and the location of use – become associated with the intense reinforcement induced by ...
The reward and punishment systems are defined as dependent, such that reward activation (the BAS) both increases responses to appetitive stimuli and decreases responses to aversive stimuli. The joint subsystems hypothesis is most applicable in real-world contexts that contain mixed stimuli: strong, weak, punishment, and reward.